Articles

Browse our published research articles

59 articles
41
Research Article DOI: 10.67579/njo.2025.mgmk2wzb

THE CONTRIBUTION OF INTESTINAL PROTOZOA TO DIARRHOEA IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY AT NATIONAL HOSPITAL ABUJA

Ayuba Hannatu U*, Festus Igbinoba, Philip Nwajiobi-Princewill, Sunday A. Adewuyi, Abbas A. Abdus-salam, Rasaaq A. Oyesegun, Simeon C. Aruah, Samuel Sonibare, Khadijah Abdulraheem, Tobechi Akujiobi, Aminu U, Omonyeme Oboh, Abdulhamid Shehu, Dalhat Umar, Amina I Dansani, Philip Ayom, Kenneth Enwerem, Nura Shuaib, Fatima Inno Uba

Background: Diarrhoea is one of the most critical health problems worldwide. In addition, vital symptom burden in cancer patients undergoing chemotherapy, which can worsen the disease condition with poor outcomes in the presence of intestinal protozoa infestations. The study assessed the contribution of intestinal protozoa to diarrhoea in breast cancer patients undergoing chemotherapy at National ...

Jul, 2025 pp. 201-207 154 views 83 downloads
42
Research Article DOI: 10.67579/njo.2026.jnyc7cxc

CHILDHOOD CANCER CONTROL IN RESOURCE-POOR SETTINGS: A NARRATIVE REVIEW OF CHALLENGES USING THE HEALTH SYSTEMS PLUS FRAMEWORK

AHMED Saleh*, Taiye T. Ibiyeye, Ngozi P. Udechukwu, Kaltumi Shuaibu, Sikemi T. Oluleye, Heather Fosburgh, Catherine G. Lam

ABSTRACT Background: Childhood cancer control in resource-poor settings faces multiple barriers across the continuum of care, from delayed diagnosis to treatment abandonment and limited survivorship support. While individual challenges are well-documented, understanding how they interact and reinforce one another is essential for designing effective interventions. The Health Systems Plus (HS+) Fra...

Jul, 2026 pp. 203-218 57 views 16 downloads
43
Research Article DOI: 10.67579/njo.2025.6gkns10p

EVALUATING ACCESS TO RADIATION ONCOLOGISTS BY NON-ONCOLOGY DOCTORS IN NIGERIA

Samuel A. Otene*, Victor E. Ekpo, Maryann E. Ekpo

Background: Radiotherapy plays a pivotal role in the multidisciplinary management of cancer, yet access to Radiation Oncologists (ROs) in low- and middle-income countries, including Nigeria, remains a challenge. While much attention has been paid to infrastructure and equipment deficits, the ease with which non-oncology physicians can access ROs is underexplored. Objective: The objectives of this ...

Jul, 2025 pp. 208-219 158 views 58 downloads
44
Research Article DOI: 10.67579/njo.2026.xy08qc97

Mucinous carcinoma upregulates targets ‎of small ‎molecule ‎inhibitors of cancers: implications ‎for ‎targeting oncogenic mucins in the colorectal cancer microenvironment

Henry Ebili*, Adesoji Ebenezer Adetona, Patrick Akintunde Akintola, Uchenna Simon Ezenkwa, Kazeem Adeyinka Adegboyejo, Ayotunde O. Ale, Yusuf Abdullahi

Background: Mucinous colorectal carcinoma (CRC) is a distinct histological subtype ‎associated with abundant extracellular mucin production, adverse clinicopathological features, ‎chemoresistance, and poor prognosis. However, the tumour microenvironment (TME) signalling ‎characteristics of mucinous CRC and its potential vulnerabilities to anti-mucin small molecule ‎inhibitors (SMIs) remain incompl...

Aug, 2026 pp. 219-241 99 views 20 downloads
45
Research Article DOI: 10.67579/njo.2025.qe8i4g5m

EFFECTIVENESS OF TRAINING WORKSHOP ON THE ATTITUDE OF HEALTHCARE PROVIDERS TOWARDS BREAKING BAD NEWS TO CANCER PATIENTS: A MULTI- INSTITUTIONAL STUDY

Samuel A. Otene*, Shehu Salihu Umar, Abba Ali Tijjani, DA Bojude D, Foluke O. Sarimiye, Sani B. Abubakar, Vitalis C. Okwor, Emmanuel Aimebelomo Ikhile, Auwal G. Suleiman, Suleiman K. Hamidu, Vivian C. Nwordu, Nwamaka Lasebikan, Musa Ali-Gombe, Usman M. Aliyu

Background: Breaking bad news (BBN) is a critical aspect of oncology care. Unfortunately, many healthcare providers (HCPs) in Nigeria lack formal training in this skill. Objective: This study evaluated the effectiveness of a training workshop on HCPs’ attitudes towards BBN to cancer patients across multiple institutions in Nigeria. Methods: A quasi-experimental study was conducted across six feder...

Jul, 2025 pp. 220-233 152 views 68 downloads
46
Research Article DOI: 10.67579/njo.2025.xstu1r2d

ASSESSMENT OF COMPLIANCE TO CHEMOTHERAPY AMONGST BREAST CANCER PATIENTS IN A RADIOTHERAPY FACILITY: A PROSPECTIVE STUDY

Gaddafi Yusuf*, Sunday A. Adewuyi, Ismail H. Zubairu

Background: Breast cancer is a leading cause of cancer-related deaths worldwide, particularly in Sub-Saharan Africa, where late-stage presentation and poor compliance with therapy are prevalent. Objective: To assess the level of compliance with chemotherapy among breast cancer patients and identify factors associated with compliance in a tertiary hospital in Northern Nigeria. Methods: A prospectiv...

Jul, 2025 pp. 234-248 149 views 94 downloads
47
Research Article DOI: 10.67579/njo.2025.awhnvbsl

EFFECT OF PSYCHOEDUCATIONAL INTERVENTION ON ANXIETY AMONG BREAST CANCER PATIENTS IN AHMADU BELLO UNIVERSITY TEACHING HOSPITAL ZARIA

Aminu Liman*, Munir Sani, Shehu Salihu Umar, Ismail H. Zubairu, Audu I. Aveka, Tajudeen A. Olasinde

Background: Breast cancer (BC) is a disease of global public health concern whose incidence is rising, leading to significant morbidity and mortality. Psychological burden associated with BC diagnosis and treatment has negative consequences on the patients in addition to physical symptoms. Many psychosocial interventions have been developed and evaluated to reduce psychological disorders such as a...

Jul, 2025 pp. 249-265 214 views 79 downloads
48
Research Article DOI: 10.67579/njo.2025.zg6ha74d

SEX DISPARITY IN CANCER OCCURRENCE AND TREATMENT AMONG CANCER PATIENTS: A 2-YEAR RETROSPECTIVE STUDY OF THE ONCOLOGY UNIT, FEDERAL TEACHING HOSPITAL, GOMBE

Khadijat A. Bobbo*, Amina U. Babuga, Zubairu S. Rayyanu, Abdulrahman Adamu, Danladi A. Bojude

Background: Sexual disparity in cancer prevalence and treatment approaches is a crucial factor in achieving effective cancer treatment and management globally. This study aimed to investigate gender-specific patterns of cancer types and treatments among patients in Nigeria. Objective: To determine the prevalence of different cancer types and associated treatment modalities, highlighting any sexual...

Jul, 2025 pp. 266-279 140 views 74 downloads
49
Research Article DOI: 10.67579/njo.2025.c5fsm2w9

PATTERN OF METASTATIC BREAST CANCER IN NIGERIA: A RETROSPECTIVE REVIEW OF CASES FROM NATIONAL HOSPITAL, ABUJA

Fatima Inno Uba*, Simeon C. Aruah, Festus Igbinoba, Rasaaq A. Oyesegun

Background: Metastatic Breast Cancer is a common presentation among breast cancer patients in Nigeria. There has been a slight decline in breast cancer mortality, which can be attributed both to the success of early detection programs and advances in treatment. Objective: To determine the pattern, sites, and outcomes of metastatic breast cancer among patients treated at the National Hospital, Abuj...

Jul, 2025 pp. 280-288 144 views 72 downloads
50
Research Article DOI: 10.67579/njo.2025.z2hnreiu

EFFECTS OF ANDROGEN DEPRIVATION THERAPY ON FASTING BLOOD GLUCOSE IN PROSTATE CANCER PATIENTS AT A TEACHING HOSPITAL IN SOUTHWESTERN NIGERIA - A PILOT STUDY

Daluchukwu J. Obi*, Chiamaka Ehiedu, Abbas A. Abdus-salam, Atara I Ntekim, Augustine Takure, Ifeanyichukwu Nwanji, Olumide Farinre, Adeniyi Adenipekun

Background: Prostate cancer is the most common cancer and the leading cause of cancer death in Nigerian men. There are many modalities of treatment of prostate cancer, among them is hormonal treatment with the use of androgen-deprivation therapy (ADT), and this has been reported to have effects on the blood glucose level, causing hyperglycaemia. Objective: To determine the effects of three-month a...

Jul, 2025 pp. 289-299 159 views 65 downloads