Articles

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59 articles
51
Research Article DOI: 10.67579/njo.2025.bfjzda3v

EFFECTS OF BRACHYTHERAPY BOOST ON PROSTATE CANCER TREATED WITH EXTERNAL BEAM RADIOTHERAPY: A PILOT STUDY

Abbas A. Abdus-salam, Olabisi T. Ojo*, Chiamaka Ehiedu, Maryam A. Bashir, Atara I Ntekim, Adewumi O. Alabi, Sharif A. Folorunso, Jimoh mutiu alani, Foluke O. Sarimiye, Adeniyi Adenipekun

Background: Prostate cancer is the leading cause of cancer amongst men in Nigeria. External beam radiotherapy (EBRT) and high-dose rate brachytherapy (HDR-BT) play a significant role in the management of localised prostate cancer. Objective: This study compared the treatment outcome of the management of intermediate and high-risk localised prostate cancer patients using EBRT alone and EBRT + BT. M...

Jul, 2025 pp. 300-312 157 views 90 downloads
52
Research Article DOI: 10.67579/njo.2025.xr23ody7

A PROGRESSIVE EMBRYONAL RHABDOMYOSARCOMA OF THE UTERINE CERVIX WITH RIGHT BREAST LUMP IN A 43-YEAR-OLD ADULT: A CASE REPORT

Amina I Dansani*, Tajudeen A. Olasinde, Olabisi T. Ojo, Aisha Mustapha, Shehu Abdullahi, Shehu Salihu Umar

Introduction: Embryonal Rhabdomyosarcoma is an uncommon type of sarcoma often seen in pediatric and adolescent patients, with the botryoid subtype being the most common. The incidence of this disease in adult females is 0.4% to 1% with the affected age group being patients in the third to fourth decade of life. It is rare in patients above 40 years in Nigeria. Case Presentation: We describe the ca...

Jul, 2025 pp. 313-320 158 views 86 downloads
53
Research Article DOI: 10.67579/njo.2025.jsg8ad20

PRIMARY FEMUR NEUROBLASTOMA IN A 16-YEAR-OLD: A CASE REPORT

Adewumi O. Alabi*, Bright A. Igbinoba, Olusola K. Idowu, Kolawole O. Aramide, Nnamdi Orah, Mohammed Y.M. Habeebu, Opeyemi I. Olusunmade, Emmanuel E. Ojiebun

The incidence of neuroblastomas in individuals aged 10 and above is less than 10%. It is also associated with poor prognosis in older children and adults. This is a case report of a 16-year-old lady with pain and swelling in the left knee. The definitive diagnosis was neuroblastoma in the left distal femur after immunohistochemistry. The patient underwent surgery and chemotherapy. Extremity neurob...

Jul, 2025 pp. 321-327 154 views 73 downloads
54
Research Article DOI: 10.67579/njo.2025.128qvl8n

CASE REPORT: A SUCCESSFULLY TREATED MYCOSIS FUNGOIDES WITH CHOP CHEMOTHERAPY REGIMEN

Fatima Inno Uba*

Introduction: Mycosis fungoides (MF) is a rare and aggressive form of cutaneous T-cell lymphoma (CTCL). It typically presents with skin lesions, but can progress to involve lymph nodes, blood and internal organs. Treatment options for MF are limited, and the disease often has a poor prognosis. Case Presentation: We report a case of a patient who presented with history of itching around the head an...

Jul, 2025 pp. 328-331 146 views 84 downloads
55
Research Article DOI: 10.67579/njo.2025.ddie0w3q

A CASE REPORT OF IFOSFAMIDE INDUCED ENCEPHALOPATHY IN THE MANAGEMENT OF METASTATIC VULVAR LEIOMYOSARCOMA IN NATIONAL HOSPITAL ABUJA

Shagaya Uchechukwu Nneka, Ayuba Hannatu U*, Paul Emeka, Abubakar M. Bello, Mohammed Nafisah Mamman, Kwapmi Nicholas N., Dalhat Umar, Anosike Agbedo

Introduction: Ifosfamide induced encephalopathy (IIE) is not a common phenomenon and is under reported in our context. Its incidence ranges between 10 to 40% in developed settings. It comprises of a range of neuropsychiatric conditions such as confusion, disorientation, somnolence, agitation, hallucinations, lethargy, and seizures. With the extensive use of ifosfamide in oncology in the management...

Jul, 2025 pp. 332-336 131 views 80 downloads
56
Research Article DOI: 10.67579/njo.2025.o8n1wdbe

SYNCHRONOUS PRIMARY CERVICAL AND COLORECTAL CANCERS IN A 25-YEAR-OLD WOMAN

Charles Okwonna*, Nafisa B. Iliyasu, Abba Ali Tijjani, Sunday A. Adewuyi, Shehu Salihu Umar

Introduction: Synchronous cancer refers to two or more malignancies co-existing in a patient at the time of diagnosis or within 6 months of diagnosing the first. Cervical cancer is the commonest gynecological malignancy in Nigeria, while colorectal cancer the 4th commonest malignancy in Nigeria. Case Presentation: We present a 25-year-old grand multi-para who presented the hospital with a 20-month...

Jul, 2025 pp. 337-343 157 views 81 downloads
57
Research Article DOI: 10.67579/njo.2025.xng8erj1

BREAST CANCER IN YOUNG ADULTS: A CASE SERIES

Ndidi Okunnuga*, Bamidele Alegbeleye, Adedotun Akinwande, Adetokunbo Adedotun Okunnuga, Adewale Ayadi, Peter Ologunagba

Introduction: Breast cancer is the most common cancer among women globally. The age at presentation is crucial and determines the type, prognosis, or outcome of treatment. We report two cases of breast cancer in young adult patients due to its rarity and the need for clinicians to have a high index of suspicion while assessing any breast tumor in such patients. Case presentation: The clinical pres...

Jul, 2025 pp. 344-355 142 views 59 downloads
58
Research Article DOI: 10.67579/njo.2025.p0oacz1j

CASE REPORT: SQUAMOUS CELL CARCINOMA OF THE BREAST

Fatima Inno Uba*

Introduction: Squamous cell carcinoma of the breast is a rare and aggressive type of cancer, accounting for less than 0.1% of all invasive breast cancers. This type of tumor is believed to arise from squamous metaplasia of ductal carcinoma cells or mammary duct epithelium. It is typically found in the skin and mucous membranes, rather than the usual glandular cells found in breast tissues. Case Pr...

Jul, 2025 pp. 356-360 146 views 63 downloads
59
Research Article DOI: 10.67579/njo.2025.yzbm93i1

CONTRASTING OUTCOMES IN BILATERAL HORMONE POSITIVE BREAST CANCER: COMPLETE PRIMARY TUMOUR REGRESSION WITH PERSISTENT NODAL METASTASIS

Ahmed Aliyu*, Ismail H. Zubairu, Abba Ali Tijjani, Halima O. Aliyu, Muhammad Daniyan, Shehu Salihu Umar

Introduction: Bilateral breast carcinoma (BBC) is an uncommon but clinically significant condition, with an incidence ranging from 1.4% to 12%. It can present synchronously or metachronously and poses diagnostic and therapeutic challenges due to its rarity and heterogeneous biological behavior. Complete primary tumor regression refers to the complete disappearance of the primary tumor at the site ...

Jul, 2025 pp. 361-365 144 views 76 downloads