Articles | Nigerian Journal of Oncology

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Research Article DOI: 10.67579/njo.2026.luhlnatt

Plasma Cadmium Concentrations Among Women with Breast Cancer in Abuja, Nigeria: A Case–Control Study

Lara Obaji_ogar^*, Augusta Nsonwu‑Anyanwu

Background Breast cancer remains the most frequently diagnosed cancer among women worldwide and a leading cause of cancer-related mortality. Environmental exposure to cadmium, a recognized human carcinogen, has been implicated in breast carcinogenesis through multiple biological mechanisms, but data from sub-Saharan Africa remain limited. Objective To compare plasma cadmium concentrations between ...

Oct, 2026 pp. 69-78 17 views 3 downloads

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Research Article DOI: 10.67579/njo.2026.e7abhcw2

Pattern of Cancers among Patients Managed at the Oncology Clinic of Jos University Teaching Hospital: A Retrospective Review

Nandul N. Maurice^*, Anil I. Sirisena

Background: Plateau State, Nigeria, has a long history of tin and columbite mining, resulting in elevated environmental concentrations of naturally occurring radioactive materials (NORMs), including uranium, thorium, and radon, as well as contamination by carcinogenic heavy metals. Although direct epidemiological evidence linking mining-related radiation exposure to cancer incidence remains limite...

Sep, 2026 pp. 78-90 22 views 3 downloads

3

Research Article DOI: 10.67579/njo.2026.37wdm8y4

Title: Sarcoma and Limb Amputation: the University College Hospital, Ibadan Experience

Olusola K. Idowu^*, Balogun Mosimabale Joe

Introduction: Sarcomas are rare malignant tumors originating from mesenchymal tissues. Despite advances in limb-sparing techniques, amputation remains a vital option for patients with extensive or non-salvageable limb sarcomas. Objective: This study investigates the demographics, surgical management, and outcomes of patients who underwent limb amputations due to sarcomas in a tertiary Nigerian hos...

Aug, 2026 pp. 179-188 26 views 10 downloads

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Research Article DOI: 10.67579/njo.2026.6g98oeab

KNOWLEDGE, USAGE, AND PERCEPTION OF GENERATIVE AI TOOLS AMONG ONCOLOGY RESIDENTS IN NIGERIA – A CROSS-SECTIONAL STUDY

Kosisochukwu Udeogu^*, Okezie Ikenna Ibeleme, Prince Chinonso Okite, Ofure Angela Ogbidi

Introduction: Artificial Intelligence (AI) has increasingly demonstrated benefits across multiple sectors, including healthcare. Despite its expanding applications, adoption of generative AI in Oncology residency training in Africa remains limited. This study assessed the knowledge, usage patterns, perceptions, and challenges associated with generative AI tools among Oncology residents in Nigeria,...

Aug, 2026 pp. 144-151 49 views 14 downloads

5

Research Article DOI: 10.67579/njo.2026.xy08qc97

Mucinous carcinoma upregulates targets ‎of small ‎molecule ‎inhibitors of cancers: implications ‎for ‎targeting oncogenic mucins in the colorectal cancer microenvironment

Henry Ebili^*, Adesoji Ebenezer Adetona, Patrick Akintunde Akintola, Uchenna Simon Ezenkwa, Kazeem Adeyinka Adegboyejo, Ayotunde O. Ale, Yusuf Abdullahi

Background: Mucinous colorectal carcinoma (CRC) is a distinct histological subtype ‎associated with abundant extracellular mucin production, adverse clinicopathological features, ‎chemoresistance, and poor prognosis. However, the tumour microenvironment (TME) signalling ‎characteristics of mucinous CRC and its potential vulnerabilities to anti-mucin small molecule ‎inhibitors (SMIs) remain incompl...

Aug, 2026 pp. 219-241 62 views 12 downloads

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Research Article DOI: 10.67579/njo.2026.77gb18rs

Assessing the Effect of Health Education on Knowledge of Breast and Cervical Cancer Among Secondary School Girls in Southeastern Nigeria

Kosisochukwu Udeogu^*, Nneoma Nwakaego Shiweobi, Chimdindu Peace Ugwuanyi, Nwamaka Lasebikan

Introduction: Breast and cervical cancers are major public health concerns in Nigeria, contributing substantially to cancer-related morbidity and mortality. Low awareness contributes to late presentation and poor outcomes. Adolescence presents an opportunity to instill preventive health behaviors, yet knowledge levels among Nigerian secondary school girls remain suboptimal. This study assessed the...

Jul, 2026 pp. 152-160 54 views 13 downloads

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Research Article DOI: 10.67579/njo.2026.jb7ksbau

Evaluating the Prevalence of Nurse-led Spiritual Care and Coping Strategies among Cancer Patients at Asi-Ukpo Cancer Centre

Oiza Tessy Ahmadu^*, Ogabor N. Godwin

Background: In Sub-Saharan Africa, where spirituality is deeply embedded in the lived experience of illness, nurse-led spiritual care holds particular relevance. Despite growing international evidence, site specific data from Nigerian oncology centres on its impact on patient coping remain scarce. Objective: To assess the prevalence of nurse-led spiritual care and faith based coping strategies of ...

Jul, 2026 pp. 129-144 67 views 19 downloads

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Research Article DOI: 10.67579/njo.2026.55xb0hh0

PATTERN OF PRESENTATION OF COLORECTAL CANCER IN A TERTIARY CARE FACILITY, SOUTHWEST NIGERIA A Ten-Year Retrospective Review

Emmanuel Aimebelomo Ikhile^*, Ayorinde M. Folasire

BACKGROUND Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide and the leading gastrointestinal malignancy globally. In Nigeria, CRC has risen from the tenth to the fourth most common cancer in a single decade, yet organized screening is virtually absent and most patients present with advanced disease. METHODS A retrospective review of 300 histologically confirmed CRC cas...

Jul, 2026 pp. 112-128 80 views 23 downloads

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Research Article DOI: 10.67579/njo.2026.6ud9ie6w

Comparative Overall Survival and Time to Progression Across Four HDR Brachytherapy Fractionation Regimens in Locally Advanced Cervical Cancer: A Retrospective Cohort Study at UCH Ibadan, Nigeria

Emmanuel Aimebelomo Ikhile^*, Ayorinde M. Folasire, Jummai Desiree Jimeta-Tuko

BACKGROUND Locally advanced cervical cancer represents the dominant presentation in sub-Saharan Africa, where radiotherapy remains the primary curative modality. High-dose-rate (HDR) intracavitary brachytherapy is an essential component of definitive chemoradiation; however, the optimal fractionation schedule in resource-limited settings remains debated. This study compared overall survival and ti...

Jul, 2026 pp. 32-42 97 views 53 downloads

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Research Article DOI: 10.67579/njo.2026.b0izg2ej

TRAVEL DISTANCE FOR RADIOTHERAPY IN NIGERIA: A RETROSPECTIVE ANALYSIS OF CASES MANAGED AT A RADIOTHERAPY CENTER. REVISED MANUSCRIPT

Nuhu Tumba^*, Sunday A. Adewuyi, Kelechi Eguzo

Background Travel distance affects access to healthcare services and can influence service utilization and patient outcomes in cancer care. In Nigeria, the limited availability of radiotherapy facilities, uneven geographical distribution, and unpredictable equipment functionality make patients to travel long distances to access treatment. Objectives This study examined the actual distance travelle...

Jul, 2026 pp. 18-31 71 views 14 downloads