Articles | Nigerian Journal of Oncology

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Research Article DOI: 10.67579/njo.2025.5wu5kovu

USE OF LOW-DOSE RATE BRACHYTHERAPY IN THE TREATMENT OF GYNAECOLOGY MALIGNANCIES IN A LOW-RESOURCE SETTING: A TENYEAR REVIEW

Charles Okwonna^*, Shehu Salihu Umar, Abba Ali Tijjani, Oiza Tessy Ahmadu, Aisha Mustapha, Aisha Jamila Ahmad, Tajudeen A. Olasinde

Introduction: Gynaecological cancers are among the most common cancers worldwide and vary in incidence geographically. In Nigeria, cervical cancer is the most common gynaecological cancer and the second most common cause of cancer-related mortality. Cervical cancer constitutes a huge percentage of the cases treated with radiotherapy in developing nations. This study aims to assess the impact of lo...

Jan, 2025 pp. 90-109 144 views 87 downloads

22

Research Article DOI: 10.67579/njo.2026.vj6wofc9

Hematological and Clinical Predictors of Survival in Cervical Cancer Patients in Nigeria: A Retrospective Cohort Study

Ajibike Orekoya, Abbas A. Abdus-salam, Adeniyi Adenipekun, Atara I Ntekim, Bolaji L. Salako

Background: Cervical cancer remains a leading cause of cancer mortality in low-resource settings. Hematological abnormalities such as anemia and leukocytosis are common and may influence prognosis. Objective: To evaluate baseline hematological profiles and their association with overall survival among cervical cancer patients treated at the Radiotherapy Clinic, University College Hospital, Ibadan,...

Jul, 2026 pp. 91-111 78 views 30 downloads

23

Research Article DOI: 10.67579/njo.2026.6thr279i

COMPARATIVE OUTCOMES OF RADIATION TREATMENT MODALITIES FOR PROSTATE CANCER IN A RESOURCE-LIMITED SETTING

Oladeji Afolabi adebayo, Ayorinde M. Folasire^*, Foluke O. Sarimiye, Chiamaka Ehiedu, Olabisi T. Ojo

Background: Prostate cancer remains a major malignancy in sub-Saharan Africa, where access to advanced radiotherapy is limited. Objective: This study compares biochemical recurrence-free survival (bRFS) and toxicity outcomes among prostate cancer patients who received external beam radiotherapy (EBRT) alone, high-dose-rate brachytherapy (HDRBT) monotherapy, or combined EBRT+HDRBT at West Africa’s ...

Feb, 2026 pp. 99-112 180 views 86 downloads

24

Research Article DOI: 10.67579/njo.2025.pcr7fzt5

DEMOGRAPHIC PROFILE AND CHEMORADIOTHERAPY TREATMENT OUTCOME OF CERVICAL CANCER PATIENTS: A LOW-RESOURCE SETTING PERSPECTIVE

Abba Ali Tijjani^*, Shehu Salihu Umar, Ibrahim Abba Tijjani, Charles Okwonna, Aminu Liman, Adamu Abdullahi, Adeniyi Adenipekun

Introduction: Cervical cancer is a leading cause of morbidity and mortality especially in developing countries with steady rise in its incidence and mortality over the years. Most women with cervical cancer in sub-Saharan Africa present late with locally advanced disease and require external beam radiotherapy and brachytherapy for effective curative treatment. Methods: The records of 243 cervical ...

Jan, 2025 pp. 110-122 185 views 80 downloads

25

Research Article DOI: 10.67579/njo.2026.55xb0hh0

PATTERN OF PRESENTATION OF COLORECTAL CANCER IN A TERTIARY CARE FACILITY, SOUTHWEST NIGERIA A Ten-Year Retrospective Review

Emmanuel Aimebelomo Ikhile^*, Ayorinde M. Folasire

BACKGROUND Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide and the leading gastrointestinal malignancy globally. In Nigeria, CRC has risen from the tenth to the fourth most common cancer in a single decade, yet organized screening is virtually absent and most patients present with advanced disease. METHODS A retrospective review of 300 histologically confirmed CRC cas...

Jul, 2026 pp. 112-128 105 views 30 downloads

26

Research Article DOI: 10.67579/njo.2026.b36ky0jz

SPIRITUALITY AND RELIGIOSITY IN ONCOLOGY: A SOCIAL STUDY OF PATIENTS’ NEEDS

Chidiebere Agbakwuru^*, Jimoh mutiu alani, Olumide Noah, Anthonia Sowunmi, Wilfred Nwachukwu

Background: Cancer diagnosis and treatment impose significant psychological and existential burdens, particularly in high-religiosity settings like Nigeria, where spirituality and religion often serve as key coping resources. This study examined spiritual well-being (SWB) and its associations with perceived relational and existential outcomes among oncology patients using a validated tool in a Nig...

Feb, 2026 pp. 113-123 183 views 86 downloads

27

Research Article DOI: 10.67579/njo.2025.8blzbtat

CAUSES, TIMING AND EFFECTS OF RADIOTHERAPY TREATMENT BREAKS IN NSIA-LUTH CANCER CENTRE

Bolanle Adegboyega^*, Mohammed Y.M. Habeebu, Adewumi O. Alabi, Mariam Bashir, Esther Adegbolagun, Adedayo Joseph, Nimotallahi Bello, Emmanuel Olufisayo, Tolulope Fashola, John Onyeji, Taiwo Afekhai, Jummai Desiree Jimeta-Tuko, Anthonia Sowunmi

Introduction: Cancer treatment includes several modalities that must be completed within specified periods to improve treatment outcome. Radiotherapy as a vital part of managing cancer demands that overall time be kept as short as possible to prevent repopulation of the cells which can affect local control and thus the overall survival of the patient. This study highlights the causes, timing, and ...

Jan, 2025 pp. 123-133 264 views 96 downloads

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Research Article DOI: 10.67579/njo.2026.mvp44bin

SQUAMOUS CELL CARCINOMA OF THE SKIN ARISING FROM A LEPROMATOUS ULCER: A CASE REPORT

Charles Okwonna^*, Mahmud Ahmed, Sunday A. Adewuyi, Adamu Abdullahi, Shehu Salihu Umar

Background: Non-melanoma skin cancers (NMSC) are among the most frequently diagnosed malignancies globally. While basal cell carcinoma predominates in fair-skinned populations, squamous cell carcinoma (SCC) is relatively more common among black populations. Chronic ulcers, including rare cases of lepromatous ulcers, may undergo malignant transformation into SCC. Case presentation: We present a cas...

Feb, 2026 pp. 124-129 163 views 90 downloads

29

Research Article DOI: 10.67579/njo.2026.jb7ksbau

Evaluating the Prevalence of Nurse-led Spiritual Care and Coping Strategies among Cancer Patients at Asi-Ukpo Cancer Centre

Oiza Tessy Ahmadu^*, Ogabor N. Godwin

Background: In Sub-Saharan Africa, where spirituality is deeply embedded in the lived experience of illness, nurse-led spiritual care holds particular relevance. Despite growing international evidence, site specific data from Nigerian oncology centres on its impact on patient coping remain scarce. Objective: To assess the prevalence of nurse-led spiritual care and faith based coping strategies of ...

Jul, 2026 pp. 129-144 93 views 26 downloads

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Research Article DOI: 10.67579/njo.2026.1e4nz1ph

RECURRENT RECTAL ADENOCARCINOMA WITH KRAS MUTATION POST-MFOLFOX6/BEVACIZUMAB REMISSION: A CASE REPORT

Yusuf Tukur^*, Abubakar M. Bello, Usman M. Aliyu, Oladapo B. Campbell, Aisha Mustapha, Abubakar Ibrahim Diggi, Yusuf Dantani, Shehu Salihu Umar

Background: This case report elucidates the clinical trajectory of a 41-year-old male diagnosed with low rectal adenocarcinoma, further complicated by pulmonary metastases, harboring a KRAS mutation, and characterized by microsatellite stability. Case Presentation: This patient demonstrated a significant and favorable response to neoadjuvant chemotherapy with a modified FOLFOX6 (mFOLFOX6) regimen ...

Feb, 2026 pp. 130-138 177 views 84 downloads