Articles | Nigerian Journal of Oncology

21

Research Article DOI: 10.67579/njo.2026.6thr279i

COMPARATIVE OUTCOMES OF RADIATION TREATMENT MODALITIES FOR PROSTATE CANCER IN A RESOURCE-LIMITED SETTING

Oladeji Afolabi adebayo, Ayorinde M. Folasire^*, Foluke O. Sarimiye, Chiamaka Ehiedu, Olabisi T. Ojo

Background: Prostate cancer remains a major malignancy in sub-Saharan Africa, where access to advanced radiotherapy is limited. Objective: This study compares biochemical recurrence-free survival (bRFS) and toxicity outcomes among prostate cancer patients who received external beam radiotherapy (EBRT) alone, high-dose-rate brachytherapy (HDRBT) monotherapy, or combined EBRT+HDRBT at West Africa’s ...

Feb, 2026 pp. 99-112 292 views 176 downloads

22

Research Article DOI: 10.67579/njo.2025.pcr7fzt5

DEMOGRAPHIC PROFILE AND CHEMORADIOTHERAPY TREATMENT OUTCOME OF CERVICAL CANCER PATIENTS: A LOW-RESOURCE SETTING PERSPECTIVE

Ali Abba Tijjani^*, Shehu Salihu Umar, Ibrahim Abba Tijjani, Charles Okwonna, Aminu Bello Liman, Adamu Abdullahi, Adeniyi Adenipekun

Introduction: Cervical cancer is a leading cause of morbidity and mortality especially in developing countries with steady rise in its incidence and mortality over the years. Most women with cervical cancer in sub-Saharan Africa present late with locally advanced disease and require external beam radiotherapy and brachytherapy for effective curative treatment. Methods: The records of 243 cervic...

Jan, 2025 pp. 110-122 324 views 156 downloads

23

Research Article DOI: 10.67579/njo.2026.55xb0hh0

PATTERN OF PRESENTATION OF COLORECTAL CANCER IN A TERTIARY CARE FACILITY, SOUTHWEST NIGERIA A Ten-Year Retrospective Review

Emmanuel Aimebelomo Ikhile^*, Ayorinde M. Folasire

BACKGROUND Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide and the leading gastrointestinal malignancy globally. In Nigeria, CRC has risen from the tenth to the fourth most common cancer in a single decade, yet organized screening is virtually absent and most patients present with advanced disease. METHODS A retrospective review of 300 histologically confirmed CRC ...

Jul, 2026 pp. 112-128 36 views 18 downloads

24

Research Article DOI: 10.67579/njo.2026.b36ky0jz

SPIRITUALITY AND RELIGIOSITY IN ONCOLOGY: A SOCIAL STUDY OF PATIENTS’ NEEDS

Chidiebere Agbakwuru^*, Jimoh mutiu alani, Noah Olumide, Anthonia Sowunmi, Wilfred Nwachukwu

Background: Cancer diagnosis and treatment impose significant psychological and existential burdens, particularly in high-religiosity settings like Nigeria, where spirituality and religion often serve as key coping resources. This study examined spiritual well-being (SWB) and its associations with perceived relational and existential outcomes among oncology patients using a validated tool in a Nig...

Feb, 2026 pp. 113-123 332 views 176 downloads

25

Research Article DOI: 10.67579/njo.2025.8blzbtat

CAUSES, TIMING AND EFFECTS OF RADIOTHERAPY TREATMENT BREAKS IN NSIA-LUTH CANCER CENTRE

Bolanle Adegboyega^*, Habeebu Muhammad, Adewumi O. Alabi, Mariam Bashir, Esther Adegbolagun, Adedayo Joseph, Nimotallahi Bello, Emmanuel Olufisayo, Tolulope Fashola, John Onyeji, Taiwo Afekhai, Jummai Desiree Jimeta-Tuko, Anthonia Sowunmi

Introduction: Cancer treatment includes several modalities that must be completed within specified periods to improve treatment outcome. Radiotherapy as a vital part of managing cancer demands that overall time be kept as short as possible to prevent repopulation of the cells which can affect local control and thus the overall survival of the patient. This study highlights the causes, timing, and ...

Jan, 2025 pp. 123-133 352 views 195 downloads

26

Research Article DOI: 10.67579/njo.2026.mvp44bin

SQUAMOUS CELL CARCINOMA OF THE SKIN ARISING FROM A LEPROMATOUS ULCER: A CASE REPORT

Charles Okwonna^*, Mahmud Ahmed, Sunday A. Adewuyi, Adamu Abdullahi, Shehu Salihu Umar

Background: Non-melanoma skin cancers (NMSC) are among the most frequently diagnosed malignancies globally. While basal cell carcinoma predominates in fair-skinned populations, squamous cell carcinoma (SCC) is relatively more common among black populations. Chronic ulcers, including rare cases of lepromatous ulcers, may undergo malignant transformation into SCC. Case presentation: We present a cas...

Feb, 2026 pp. 124-129 273 views 177 downloads

27

Research Article DOI: 10.67579/njo.2026.jb7ksbau

Evaluating the Prevalence of Nurse-led Spiritual Care and Coping Strategies among Cancer Patients at Asi-Ukpo Cancer Centre

Oiza Tessy Ahmadu^*, Ogabor N. Godwin

Background: In Sub-Saharan Africa, where spirituality is deeply embedded in the lived experience of illness, nurse-led spiritual care holds particular relevance. Despite growing international evidence, site specific data from Nigerian oncology centres on its impact on patient coping remain scarce. Objective: To assess the prevalence of nurse-led spiritual care and faith based coping strategies of...

Jul, 2026 pp. 129-144 40 views 16 downloads

28

Research Article DOI: 10.67579/njo.2026.1e4nz1ph

RECURRENT RECTAL ADENOCARCINOMA WITH KRAS MUTATION POST-MFOLFOX6/BEVACIZUMAB REMISSION: A CASE REPORT

Yusuf Tukur^*, Abubakar M. Bello, Usman M. Aliyu, Oladapo B. Campbell, Aisha Mustapha, Abubakar Ibrahim Diggi, Yusuf Dantani, Shehu Salihu Umar

Background: This case report elucidates the clinical trajectory of a 41-year-old male diagnosed with low rectal adenocarcinoma, further complicated by pulmonary metastases, harboring a KRAS mutation, and characterized by microsatellite stability. Case Presentation: This patient demonstrated a significant and favorable response to neoadjuvant chemotherapy with a modified FOLFOX6 (mFOLFOX6) regimen ...

Feb, 2026 pp. 130-138 277 views 173 downloads

29

Research Article DOI: 10.67579/njo.2025.a5ebkloc

CASE REPORT: A RARE CASE OF BREAST METASTASIS FROM MUCINOUS RECTAL CARCINOMA

Okonkwo Maryjane Chioma^*, DA Bojude D, Ayuba Hannatu U, A Lawan, AU Usman, Z Usman

Introduction: There are few cases of breast metastases from colorectal cancer (CRC). The most common sites of metastases of colorectal cancer are the liver, lungs and the peritoneum. Breast metastases from colorectal cancers are very rare and metastases to distant sites signify a very poor prognosis. We report a case of a chemotherapy and radiotherapy treatment naive patient who presented with ...

Jan, 2025 pp. 134- 138 233 views 132 downloads

30

Research Article DOI: 10.67579/njo.2025.uk2a9tap

METASTATIC BREAST CARCINOMA TO THE MANDIBLE: A CASE REPORT

Bolanle Adegboyega^*, Adegbayi Adekunle, John Omomila, Emeka Aforka, Adewumi O. Alabi, Sunday A. Adewuyi

Introduction: Breast cancer is a leading cause of cancer-related mortality in women globally, especially in low and middle-income countries due to late presentation and limited access to specialized care. Metastatic spread significantly impacts morbidity and mortality rates. While metastasis in breast cancer commonly targets organs such as the lungs, liver, bones, brain and pleural; occurrences in...

Jan, 2025 pp. 139-143 315 views 148 downloads