Volume 1

Volume 1 (2025)

Published in 2025

Issues in this Volume

Issue 2 (July)

Issue 1 (January)

Articles in this Volume

31 articles
1
Research Article

CASE REPORT: SQUAMOUS CELL CARCINOMA OF THE BREAST

Fatima Inno Uba*

Introduction: Squamous cell carcinoma of the breast is a rare and aggressive type of cancer, accounting for less than 0.1% of all invasive breast cancers. This type of tumor is believed to arise from squamous metaplasia of ductal carcinoma cells or mammary duct epithelium. It is typically found in the skin and mucous membranes, rather than the usual glandular cells found in breast tissues.Case Pre...

Jul, 2025 pp. 356-360
2
Research Article

EVALUATING ACCESS TO RADIATION ONCOLOGISTS BY NON-ONCOLOGY DOCTORS IN NIGERIA

Samuel A. Otene*, Victor E. Ekpo, Maryann E. Ekpo

Background: Radiotherapy plays a pivotal role in the multidisciplinary management of cancer, yet access to Radiation Oncologists (ROs) in low- and middle-income countries, including Nigeria, remains a challenge. While much attention has been paid to infrastructure and equipment deficits, the ease with which non-oncology physicians can access ROs is underexplored.Objective: The objectives of this s...

Jul, 2025 pp. 208-219
3
Research Article

CASE REPORT: A SUCCESSFULLY TREATED MYCOSIS FUNGOIDES WITH CHOP CHEMOTHERAPY REGIMEN

Fatima I. Uba*

Introduction: Mycosis fungoides (MF) is a rare and aggressive form of cutaneous T-cell lymphoma (CTCL). It typically presents with skin lesions, but can progress to involve lymph nodes, blood and internal organs. Treatment options for MF are limited, and the disease often has a poor prognosis.Case Presentation: We report a case of a patient who presented with history of itching around the head and...

Jul, 2025 pp. 328-331
4
Research Article

PATTERN OF METASTATIC BREAST CANCER IN NIGERIA: A RETROSPECTIVE REVIEW OF CASES FROM NATIONAL HOSPITAL, ABUJA

Fatima Inno Uba*, Simeon C. Aruah, Festus Igbinoba, Rasaaq A. Oyesegun

Background: Metastatic Breast Cancer is a common presentation among breast cancer patients in Nigeria. There has been a slight decline in breast cancer mortality, which can be attributed both to the success of early detection programs and advances in treatment.Objective: To determine the pattern, sites, and outcomes of metastatic breast cancer among patients treated at the National Hospital, Abuja...

Jul, 2025 pp. 280-288
5
Research Article

CONTRASTING OUTCOMES IN BILATERAL HORMONE POSITIVE BREAST CANCER: COMPLETE PRIMARY TUMOUR REGRESSION WITH PERSISTENT NODAL METASTASIS

Ahmed Aliyu*, Ismail H. Zubairu, Ali Abba Tijjani, Halima O. Aliyu, Muhammad Daniyan, Shehu Salihu Umar

Introduction: Bilateral breast carcinoma (BBC) is an uncommon but clinically significant condition, with an incidence ranging from 1.4% to 12%. It can present synchronously or metachronously and poses diagnostic and therapeutic challenges due to its rarity and heterogeneous biological behavior. Complete primary tumor regression refers to the complete disappearance of the primary tumor at the site ...

Jul, 2025 pp. 361-365
6
Research Article

BREAST CANCER IN YOUNG ADULTS: A CASE SERIES

Ndidi Okunnuga*, Bamidele Alegbeleye, Adedotun Akinwande, Adetokunbo Okunnuga, Adewale Ayadi, Peter Ologunagba

Introduction: Breast cancer is the most common cancer among women globally. The age at presentation is crucial and determines the type, prognosis, or outcome of treatment. We report two cases of breast cancer in young adult patients due to its rarity and the need for clinicians to have a high index of suspicion while assessing any breast tumor in such patients.Case presentation: The clinical prese...

Jul, 2025 pp. 344-355
7
Research Article

SYNCHRONOUS PRIMARY CERVICAL AND COLORECTAL CANCERS IN A 25-YEAR-OLD WOMAN

Charles Okwonna*, Nafisa B. Iliyasu, Ali Abba Tijjani, Sunday A. Adewuyi, Shehu Salihu Umar

Introduction: Synchronous cancer refers to two or more malignancies co-existing in a patient at the time of diagnosis or within 6 months of diagnosing the first. Cervical cancer is the commonest gynecological malignancy in Nigeria, while colorectal cancer the 4th commonest malignancy in Nigeria.Case Presentation: We present a 25-year-old grand multi-para who presented the hospital with a 20-month ...

Jul, 2025 pp. 337-343
8
Research Article

A CASE REPORT OF IFOSFAMIDE INDUCED ENCEPHALOPATHY IN THE MANAGEMENT OF METASTATIC VULVAR LEIOMYOSARCOMA IN NATIONAL HOSPITAL ABUJA

Shagaya Uchechukwu Nneka, Ayuba Hannatu Usman*, Paul Emeka, Bello Abubakar Mohammed, Mohammed Nafisah Mamman, Kwapmi Nicholas, Umar Farouk Dalhat, Anosike Agbedo

Introduction: Ifosfamide induced encephalopathy (IIE) is not a common phenomenon and is under reported in our context. Its incidence ranges between 10 to 40% in developed settings. It comprises of a range of neuropsychiatric conditions such as confusion, disorientation, somnolence, agitation, hallucinations, lethargy, and seizures. With the extensive use of ifosfamide in oncology in the management...

Jul, 2025 pp. 332-336
9
Research Article

PRIMARY FEMUR NEUROBLASTOMA IN A 16-YEAR-OLD: A CASE REPORT

Adewumi O. Alabi*, Bright A. Igbinoba, Oluseyi K. Idowu, Kolawole O. Aramide, Nnamdi Orah, Mohammed Y.M. Habeebu, Opeyemi I. Olusunmade, Emmanuel E. Ojiebun

The incidence of neuroblastomas in individuals aged 10 and above is less than 10%. It is also associated with poor prognosis in older children and adults. This is a case report of a 16-year-old lady with pain and swelling in the left knee. The definitive diagnosis was neuroblastoma in the left distal femur after immunohistochemistry. The patient underwent surgery and chemotherapy. Extremity neurob...

Jul, 2025 pp. 321-327
10
Research Article

A PROGRESSIVE EMBRYONAL RHABDOMYOSARCOMA OF THE UTERINE CERVIX WITH RIGHT BREAST LUMP IN A 43-YEAR-OLD ADULT: A CASE REPORT

Amina I Dansani*, Tajudeen A. Olasinde, Olabisi T. Ojo, Aisha Mustapha, Shehu Abdullahi, Shehu Salihu Umar

Introduction: Embryonal Rhabdomyosarcoma is an uncommon type of sarcoma often seen in pediatric and adolescent patients, with the botryoid subtype being the most common. The incidence of this disease in adult females is 0.4% to 1% with the affected age group being patients in the third to fourth decade of life. It is rare in patients above 40 years in Nigeria.Case Presentation: We describe the cas...

Jul, 2025 pp. 313-320
11
Research Article

EFFECTS OF BRACHYTHERAPY BOOST ON PROSTATE CANCER TREATED WITH EXTERNAL BEAM RADIOTHERAPY: A PILOT STUDY

Abbas A. Abdus-salam*, Olabisi T. Ojo, Chiamaka G. Ehiedu, Maryam A. Bashir, Atara I Ntekim, Adewumi O. Alabi, Sharif A. Folorunso, Mutiu A Jimoh, Foluke O. Sarimiye, Adeniyi A Adenipekun

Background: Prostate cancer is the leading cause of cancer amongst men in Nigeria. External beam radiotherapy (EBRT) and high-dose rate brachytherapy (HDR-BT) play a significant role in the management of localised prostate cancer.Objective: This study compared the treatment outcome of the management of intermediate and high-risk localised prostate cancer patients using EBRT alone and EBRT + BT.Met...

Jul, 2025 pp. 300-312
12
Research Article

EFFECTS OF ANDROGEN DEPRIVATION THERAPY ON FASTING BLOOD GLUCOSE IN PROSTATE CANCER PATIENTS AT A TEACHING HOSPITAL IN SOUTHWESTERN NIGERIA - A PILOT STUDY

Daluchukwu J. Obi*, Chiamaka G. Ehiedu, Abbas A Abdus-Salam, Atara I Ntekim, Augustine Takure, Ifeanyichukwu Nwanji, Olumide Farinre, Adeniyi A Adenipekun

Background: Prostate cancer is the most common cancer and the leading cause of cancer death in Nigerian men. There are many modalities of treatment of prostate cancer, among them is hormonal treatment with the use of androgen-deprivation therapy (ADT), and this has been reported to have effects on the blood glucose level, causing hyperglycaemia.Objective: To determine the effects of three-month ad...

Jul, 2025 pp. 289-299
13
Research Article

EFFECT OF PSYCHOEDUCATIONAL INTERVENTION ON ANXIETY AMONG BREAST CANCER PATIENTS IN AHMADU BELLO UNIVERSITY TEACHING HOSPITAL ZARIA

Aminu Bello Liman*, Munir Sani, Shehu Salihu Umar, Ismail H. Zubairu, Audu I. Aveka, Tajudeen A. Olasinde

Background: Breast cancer (BC) is a disease of global public health concern whose incidence is rising, leading to significant morbidity and mortality. Psychological burden associated with BC diagnosis and treatment has negative consequences on the patients in addition to physical symptoms. Many psychosocial interventions have been developed and evaluated to reduce psychological disorders such as a...

Jul, 2025 pp. 249-265
14
Research Article

SEX DISPARITY IN CANCER OCCURRENCE AND TREATMENT AMONG CANCER PATIENTS: A 2-YEAR RETROSPECTIVE STUDY OF THE ONCOLOGY UNIT, FEDERAL TEACHING HOSPITAL, GOMBE

Khadijat A. Bobbo*, Amina U. Babuga, Zubairu S. Rayyanu, Abdulrahman Adamu, Danladi A. Bojude

Background: Sexual disparity in cancer prevalence and treatment approaches is a crucial factor in achieving effective cancer treatment and management globally. This study aimed to investigate gender-specific patterns of cancer types and treatments among patients in Nigeria.Objective: To determine the prevalence of different cancer types and associated treatment modalities, highlighting any sexual ...

Jul, 2025 pp. 266-279
15
Research Article

ASSESSMENT OF COMPLIANCE TO CHEMOTHERAPY AMONGST BREAST CANCER PATIENTS IN A RADIOTHERAPY FACILITY: A PROSPECTIVE STUDY

Gaddafi Yusuf*, Sunday A. Adewuyi, Ismail H. Zubairu

Background: Breast cancer is a leading cause of cancer-related deaths worldwide, particularly in Sub-Saharan Africa, where late-stage presentation and poor compliance with therapy are prevalent.Objective: To assess the level of compliance with chemotherapy among breast cancer patients and identify factors associated with compliance in a tertiary hospital in Northern Nigeria.Methods: A prospective ...

Jul, 2025 pp. 234-248
16
Research Article

EFFECTIVENESS OF TRAINING WORKSHOP ON THE ATTITUDE OF HEALTHCARE PROVIDERS TOWARDS BREAKING BAD NEWS TO CANCER PATIENTS: A MULTI- INSTITUTIONAL STUDY

Samuel A. Otene*, Shehu Salihu Umar, Ali Abba Tijjani, DA Bojude D, Foluke O. Sarimiye, Sani B. Abubakar, Vitalis C. Okwor, Emmanuel A. Ikhile, Auwal G. Suleiman, Suleiman K. Hamidu, Vivian C. Nwordu, Nwamaka Lasebikan, Musa Ali-Gombe, Usman M. Aliyu

Background: Breaking bad news (BBN) is a critical aspect of oncology care. Unfortunately, many healthcare providers (HCPs) in Nigeria lack formal training in this skill.Objective: This study evaluated the effectiveness of a training workshop on HCPs’ attitudes towards BBN to cancer patients across multiple institutions in Nigeria.Methods: A quasi-experimental study was conducted across six federal...

Jul, 2025 pp. 220-233
17
Research Article

THE CONTRIBUTION OF INTESTINAL PROTOZOA TO DIARRHOEA IN CANCER PATIENTS UNDERGOING CHEMOTHERAPY AT NATIONAL HOSPITAL ABUJA

Ayuba Hannatu U*, Festus Igbinoba, Philip Nwajiobi-Princewill, Sunday A. Adewuyi, Abbas A Abdus-Salam, Rasaaq A. Oyesegun, Simeon C. Aruah, Samuel Sonibare, Khadijah Abdulraheem, Tobechi Akujiobi, Aminu U, Omonyeme Oboh, Abdulhamid Shehu, Dalhat Umar, Amina Dansani, Philip Ayom, Kenneth Enwerem, Nura Shuaib, Fatima I Uba

Background: Diarrhoea is one of the most critical health problems worldwide. In addition, vital symptom burden in cancer patients undergoing chemotherapy, which can worsen the disease condition with poor outcomes in the presence of intestinal protozoa infestations. The study assessed the contribution of intestinal protozoa to diarrhoea in breast cancer patients undergoing chemotherapy at National ...

Jul, 2025 pp. 201-207
18
Research Article

CANCER PATIENTS AND BLOOD TRANSFUSION DEMAND IN A RESOURCE-CONSTRAINED SETTING: A RETROSPECTIVE STUDY

Oiza T. Ahmadu*, Shehu Salihu Umar, Sani Awwalu, Albert M. Alfred, Aminu B. Liman, Gaddafi Yusuf, Mustapha I. Aliyu, Muhammad Salihu, Munir Sani, Arinze A. Mbanusi, Tajudeen A. Olasinde

Background: Cancer patients on treatment have anaemia as a common complication resulting from deceased red blood cell production, increased destruction of circulating red blood cells or bleeding from cancer. Blood transfusion in cancer patients is quite frequent as a hospital-based study demonstrated that 34% of blood donated in a health facility were transfused to cancer patients.Objective: This ...

Jul, 2025 pp. 189-200
19
Research Article

CANCER PATIENT TRENDS AND EXCESS LIFETIME CANCER RISK: A COMPARATIVE STUDY OF JOS NORTH AND SOUTH AT JUTH ONCOLOGY CLINIC

Stephen D Pam*, Nandul N. Maurice, Anil I. Sirisena, Kyermang K. Dakok, Barnabas Dauda, Ishaya Habila

Background: The Oncology Clinic at Jos University Teaching Hospital has observed a significant influx of cancer patients residing in Jos North and Jos South Local Government Areas in Plateau State with a rich history of mining activities spanning several decades. This observation prompted this study.Objective: The aim of this study was to assess the excess lifetime cancer risk (ELCR) for residents...

Jul, 2025 pp. 178-188
20
Research Article

THE ROLE OF SOCIOECONOMIC STATUS IN ACCESS TO CANCER TREATMENT AND OUTCOMES IN NORTHERN NIGERIA

Mohammed S Suleiman*, HUSSAINI MOHAMMED

Background: Cancer represents a significant public health challenge worldwide, with disparities in access to care and outcomes particularly pronounced in low-and-middle income countries. In Northern Nigeria, socioeconomic status (SES) serves as a critical determinant of access to cancer treatment and survival outcomes. Methods: This study qualitatively explores the intricate relationship betwee...

Jul, 2025 pp. 164-177
21
Research Article

OUTCOME OF MANAGEMENT OF CERVICAL CANCER PATIENTS IN A TERTIARY HOSPITAL IN SOUTH WESTERN, NIGERIA

Ajibike A. Orekoya*, Adeniyi A Adenipekun, Abbas A Abdus-Salam, Atara I Ntekim, Babatunde O Ogunnorin, Adebayo A Oladeji, Mutiu A Jimoh, Foluke O. Sarimiye, Adeniyi A Olabumuyi, Bolaji Salako, Sharif A. Folorunso, Ayorinde M Folasire

Introduction: Cervical cancer is the second most common cancer among women in Nigeria and is rated as the fourth most prevalent worldwide. While improved survival rates have occurred in high-income countries, consequent to wide screening and adequate treatment, survival remains poor in low-income countries, including Nigeria. Objective: This study aimed to determine the survival rates of cervical ...

Jan, 2025 pp. 30-51
22
Research Article

RETHINKING OPPORTUNISTIC CERVICAL CANCER SCREENING IN RESOURCE-LIMITED SETTINGS: A TEN-YEAR REVIEW OF SCREENING AT BINGHAM UNIVERSITY TEACHING HOSPITAL, JOS, NIGERIA

Nuhu Tumba*, Mbwas Mashor, Onyeka Tina Ubanyi, Timothy Ataguba Achema, John Onyeji, James Bitrus

Background: Cervical cancer is the most common gynaecological cancer affecting women in Nigeria. Despite the availability of screening methods for precancerous lesions, screening is largely opportunistic and hospital-based in Nigeria. Objectives: This study aimed to determine the prevalence and patterns of cervical dysplasia among women in a tertiary health facility in North Central Nigeria. ...

Jan, 2025 pp. 1-11
23
Research Article

ASSESSMENT OF DELAYS AMONGST CERVICAL CANCER PATIENTS IN A RADIOTHERAPY FACILITY: A PROSPECTIVE STUDY

Shehu Salihu Umar*, Adamu Abdullahi, Aisha Jamila Ahmad, Oiza Tessy Ahmadu, Anisa Yahya

Introduction: Globally, cervical cancer is the 8th commonest malignancy and the fourth commonest in females. However, in Sub-Saharan Africa, the incidence and mortality from cervical cancer is second only to breast cancer, and actually highest in some of the countries. Most cases of cervical cancer in Sub-Saharan Africa are diagnosed at advanced stages, largely due to the various delays. These inc...

Jan, 2025 pp. 70-89
24
Research Article

METASTATIC BREAST CARCINOMA TO THE MANDIBLE: A CASE REPORT

Bolanle Adegboyega*, Adegbayi Adekunle, John Omomila, Emeka Aforka, Adewumi Alabi, Sunday Adewuyi

Introduction: Breast cancer is a leading cause of cancer-related mortality in women globally, especially in low and middle-income countries due to late presentation and limited access to specialized care. Metastatic spread significantly impacts morbidity and mortality rates. While metastasis in breast cancer commonly targets organs such as the lungs, liver, bones, brain and pleural; occurrences in...

Jan, 2025 pp. 139-143
25
Research Article

CASE REPORT: A RARE CASE OF BREAST METASTASIS FROM MUCINOUS RECTAL CARCINOMA

Okonkwo Maryjane Chioma*, DA Bojude D, Ayuba Hannatu U, A Lawan, AU Usman, Z Usman

Introduction: There are few cases of breast metastases from colorectal cancer (CRC). The most common sites of metastases of colorectal cancer are the liver, lungs and the peritoneum. Breast metastases from colorectal cancers are very rare and metastases to distant sites signify a very poor prognosis. We report a case of a chemotherapy and radiotherapy treatment naive patient who presented with ...

Jan, 2025 pp. 134- 138
26
Research Article

CAUSES, TIMING AND EFFECTS OF RADIOTHERAPY TREATMENT BREAKS IN NSIA-LUTH CANCER CENTRE

Bolanle Adegboyega*, Habeebu Muhammad, Adewumi Alabi, Mariam Bashir, Esther Adegbolagun, Adedayo Joseph, Nimotallahi Bello, Emmanuel Olufisayo, Tolulope Fashola, John Onyeji, Taiwo Afekhai, Desiree Jimeta-Tuko, Anthonia Sowunmi

Introduction: Cancer treatment includes several modalities that must be completed within specified periods to improve treatment outcome. Radiotherapy as a vital part of managing cancer demands that overall time be kept as short as possible to prevent repopulation of the cells which can affect local control and thus the overall survival of the patient. This study highlights the causes, timing, and ...

Jan, 2025 pp. 123-133
27
Research Article

DEMOGRAPHIC PROFILE AND CHEMORADIOTHERAPY TREATMENT OUTCOME OF CERVICAL CANCER PATIENTS: A LOW-RESOURCE SETTING PERSPECTIVE

Ali Abba Tijjani*, Shehu Salihu Umar, Ibrahim Abba Tijjani, Charles Okwonna, Aminu Bello Liman, Adamu Abdullahi, Adeniyi A Adenipekun

Introduction: Cervical cancer is a leading cause of morbidity and mortality especially in developing countries with steady rise in its incidence and mortality over the years. Most women with cervical cancer in sub-Saharan Africa present late with locally advanced disease and require external beam radiotherapy and brachytherapy for effective curative treatment. Methods: The records of 243 cervic...

Jan, 2025 pp. 110-122
28
Research Article

USE OF LOW-DOSE RATE BRACHYTHERAPY IN THE TREATMENT OF GYNAECOLOGY MALIGNANCIES IN A LOW-RESOURCE SETTING: A TENYEAR REVIEW

Charles Okwonna*, Shehu Salihu Umar, Ali Abba Tijjani, Oiza Tessy Ahmadu, Aisha Mustapha, Aisha Jamila Ahmad, Tajudeen A. Olasinde

Introduction: Gynaecological cancers are among the most common cancers worldwide and vary in incidence geographically. In Nigeria, cervical cancer is the most common gynaecological cancer and the second most common cause of cancer-related mortality. Cervical cancer constitutes a huge percentage of the cases treated with radiotherapy in developing nations. This study aims to assess the impact of lo...

Jan, 2025 pp. 90-109
29
Research Article

SCINTIGRAPHIC PATTERN OF SKELETAL METASTASIS BASED ON MOLECULAR SUBTYPES OF BREAST CANCER AT THE DR GEORGE MUKHARI ACADEMIC HOSPITAL GARANKUWA, SOUTH AFRICA

Oiza Tessy Ahmadu*, Shehu Salihu Umar, Saad A Ahmed, Aminu Bello Liman, Trevor Mdaka

Introduction: The presence of metastasis is the most important factor affecting overall survival of patients with breast cancer. Though tremendous progress has been made in area of treatment, 20-30% of patients will develop metastasis, with the skeleton as one of the major sites of distant spread. There is marked variability among breast cancer patients who develop metastasis including the pattern...

Jan, 2025 pp. 60-69
30
Research Article

A COMPARATIVE PILOT STUDY OF A FIVE BLADE SPECULUM (BOUQUET SPECULUM) AND TWO- BLADE TRADITIONAL VAGINAL SPECULUM: PATIENT COMFORTABILITY VERSUS CERVIX VISUALIZATION

Ayuba Hannatu U*, Lawal Hanafi B, Mahmoud R.A, Akintola O.S, Fatona K.O, Aminu U

Introduction: The vaginal speculum is an important tool used in cervical cancer prevention and control. This study compared patients' comfort, cervical visualization and ease of using the bouquet speculum to the traditional bivalve vaginal speculum during the cervical cancer screening procedure at National Hospital Abuja. Due to the need to improve cervical cancer screening attendance, exploring t...

Jan, 2025 pp. 52-59
31
Research Article

AWARENESS AND KNOWLEDGE OF CERVICAL CANCER AND UTILISATION OF ITS SCREENING SERVICES AMONG FEMALE HEALTHCARE PROVIDERS IN PRIMARY HEALTH CARE CENTRES IN SOKOTO METROPOLI

Bilkisu Gulma Abubakar*, Aminu Umar Kaoje, Abdussamad Yargamji Garba, Kabir Mukhtar, Niimah Rabiu Sarkin Bauchi, Zaharaddeen Shuaibu Babandi

Introduction: Cervical cancer (CaCx) is the most common genital tract malignancy among women in Sokoto State. Lack of awareness about CaCx among health care workers is among the factors that contribute to the high burden in developing countries. This study assessed the awareness and knowledge of CaCx and the utilization of its screening services among female healthcare providers in primary healthc...

Jan, 2025 pp. 12-29
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