Volume 2, Issue 1 (February)

Articles in this Issue

11 articles
1
Research Article DOI: 10.67579/njo.2026.xabxossl

CLINICOPATHOLOGICAL CHARACTERISTICS OF BREAST CANCER PATIENTS WHO PRESENTED AT A SOUTHWESTERN NIGERIAN RADIATION ONCOLOGY CLINIC

Bolaji L. Salako, Abbas A Abdus-Salam, Ajibike A. Orekoya*, Adeniyi A Olabumuyi, Sharif A. Folorunso, Adeniyi Adenipekun, Atara I Ntekim, Babatunde O Ogunnorin, Oladeji Afolabi adebayo, Jimoh mutiu alani, Foluke O. Sarimiye, Ayorinde M. Folasire

Background: Breast cancer is the commonest female cancer in Nigeria and is also the commonest cause of cancer mortality among Nigerian females. Although the incidence is not as high as the average worldwide incidence rate, the mortality of breast cancer patients in Nigeria is high. Objective: We analysed the sociodemographic and clinicopathological characteristics of breast cancer patients who pre...

Feb, 2026 pp. 1-14 358 views 131 downloads
2
Research Article DOI: 10.67579/njo.2026.agivs4uc

HPV VACCINATION IN NIGERIA: LESSONS AND RECOMMENDATIONS FROM THE SUCCESSES OF HPV VACCINATION IN THE UNITED STATES

Adeola O. Fakolade*, Abimbola Fapohunda, Amanda Yad-El Ugboji, Valentina Ijeoma Akpa, Moyosore Adegboye, Oge Ilegbune

Human Papilloma Virus (HPV) is one of the most common sexually transmitted infections (STIs) and has been implicated in many cancers, including cervical cancer. Cervical cancer is primarily caused by persistent infection of various high-risk HPV types, and HPV vaccination is a vital and cost-effective tool in preventing HPV infections, thereby reducing the burden of cervical cancer. The HPV vaccin...

Feb, 2026 pp. 15-28 475 views 142 downloads
3
Research Article DOI: 10.67579/njo.2026.qa90k046

OUTCOME OF HEAD AND NECK CANCER PATIENTS MANAGED WITH CHEMORADIATION AT THE RADIOTHERAPY DEPARTMENT NATIONAL HOSPITAL, ABUJA (A FIVE-YEAR RETROSPECTIVE STUDY)

Fatima Inno Uba*, Simeon C. Aruah, Festus Igbinoba, Rasaaq A. Oyesegun

Background: The term ‘Head and Neck Cancer’ usually refers to squamous cell carcinomas that affect the head and neck regions of the body. However, other histologies are also found in these regions. Objective: This study assessed the outcome of head and neck cancer patients managed with chemoradiation. Methods: A data extraction form was used to obtain sociodemographic and clinical variables from t...

Feb, 2026 pp. 29-38 310 views 227 downloads
4
Research Article DOI: 10.67579/njo.2026.i4mh86kp

HEALTH-SYSTEM DETERMINANTS OF RETINOBLASTOMA OUTCOMES: A STRUCTURED AUDIT OF DIAGNOSTIC, THERAPEUTIC, AND SUPPORTIVE RESOURCES RELATIVE TO SIOP STANDARDS

Edak Ezeanosike*, Nneka Ogbu, Kene Joe-Akunne, Amarachi Okpara, Chinonye Ngwu, June Azu-Okeke

Background: Retinoblastoma is the most common intraocular malignancy of childhood and is highly curable when detected early, with survival exceeding 95% in high-income countries. In many low- and middle-income countries (LMICs), survival remains below 40% due to systemic and cultural barriers. Although the International Society of Paediatric Oncology (SIOP) defines minimum standards for manpower a...

Feb, 2026 pp. 39-54 263 views 157 downloads
5
Research Article DOI: 10.67579/njo.2026.qs7fry39

DEVELOPING CAPACITY OF PRIMARY HEALTH CENTRES IN SCREENING, EARLY DIAGNOSIS AND APPROPRIATE REFERRAL OF CERVICAL CANCER IN A LOW-RESOURCE SETTING: A PILOT INTERVENTIONAL STUDY

Shehu Salihu Umar*, Aisha Jamila Ahmad, Anisa Yahya, Mus’ab M. Dalhat, Kabiru Adamu, Khadija M. Kanoma, Zaharaddeen Shuaibu Babandi, Muazu Abdus-Salam, Benjamin O. Popoola

Background: Despite cervical cancer being preventable and treatable if detected early, it is predominantly characterised by late presentation with advanced disease in low-resource settings. This is due to a poor level of awareness of cervical cancer in the population. The Primary Health Centres (PHCs), which constitute 85.4% of all registered health facilities in Nigeria, serve as the first level ...

Feb, 2026 pp. 55-72 373 views 217 downloads
6
Research Article DOI: 10.67579/njo.2026.g1reavco

EVALUATION OF SCREENING MAMMOGRAPHY RESULTS IN A COHORT OF FEMALE HEALTH CARE WORKERS AT THE FEDERAL MEDICAL CENTER, ABUJA, NIGERIA

Oiza Tessy Ahmadu*, Uchechukwu E. Nwokwu, Olayinka B. Popoola, Adaugo C. Iheanacho, Lateef Lawal, Amarachi. N. Onyebuchi, Rahama Y. Tahir, Tolulope Oloyede, Saad A Ahmed

Background: Mammographic screening has significantly reduced breast cancer mortality in developed countries. However, data on screening outcomes in asymptomatic populations in Nigeria remain limited. Objective: To determine the distribution of BI-RADS categories and breast density patterns among asymptomatic women undergoing screening mammography at Federal Medical Centre, Abuja, Nigeria. Methods:...

Feb, 2026 pp. 73-86 375 views 165 downloads
7
Research Article DOI: 10.67579/njo.2026.vpethnkx

ACUTE TOXICITY PROFILE OF CERVICAL AND UTERINE CANCER PATIENTS TREATED WITH CHEMORADIATION: A 10-YEAR REVIEW

Yusuf Tukur*, Usman M. Aliyu, Abubakar M. Bello, Sunday A. Adewuyi, Oladapo B. Campbell, Aisha Mustapha, Yusuf Dantani, Ibrahim A. Umar, Shehu Salihu Umar

Background: Radiation therapy is integral to treating many gynaecologic cancers.Objective: We sought to determine the frequency and severity of acute toxicity in patients who had pelvic radiotherapy for cervical and uterine cancers.Methods: A retrospective study of all women who had pelvic radiation for cervical and uterine cancers at Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria,...

Feb, 2026 pp. 87-98 271 views 207 downloads
8
Research Article DOI: 10.67579/njo.2026.6thr279i

COMPARATIVE OUTCOMES OF RADIATION TREATMENT MODALITIES FOR PROSTATE CANCER IN A RESOURCE-LIMITED SETTING

Oladeji Afolabi adebayo, Ayorinde M. Folasire*, Foluke O. Sarimiye, Chiamaka Ehiedu, Olabisi T. Ojo

Background: Prostate cancer remains a major malignancy in sub-Saharan Africa, where access to advanced radiotherapy is limited. Objective: This study compares biochemical recurrence-free survival (bRFS) and toxicity outcomes among prostate cancer patients who received external beam radiotherapy (EBRT) alone, high-dose-rate brachytherapy (HDRBT) monotherapy, or combined EBRT+HDRBT at West Africa’s ...

Feb, 2026 pp. 99-112 293 views 176 downloads
9
Research Article DOI: 10.67579/njo.2026.b36ky0jz

SPIRITUALITY AND RELIGIOSITY IN ONCOLOGY: A SOCIAL STUDY OF PATIENTS’ NEEDS

Chidiebere Agbakwuru*, Jimoh mutiu alani, Noah Olumide, Anthonia Sowunmi, Wilfred Nwachukwu

Background: Cancer diagnosis and treatment impose significant psychological and existential burdens, particularly in high-religiosity settings like Nigeria, where spirituality and religion often serve as key coping resources. This study examined spiritual well-being (SWB) and its associations with perceived relational and existential outcomes among oncology patients using a validated tool in a Nig...

Feb, 2026 pp. 113-123 333 views 176 downloads
10
Research Article DOI: 10.67579/njo.2026.mvp44bin

SQUAMOUS CELL CARCINOMA OF THE SKIN ARISING FROM A LEPROMATOUS ULCER: A CASE REPORT

Charles Okwonna*, Mahmud Ahmed, Sunday A. Adewuyi, Adamu Abdullahi, Shehu Salihu Umar

Background: Non-melanoma skin cancers (NMSC) are among the most frequently diagnosed malignancies globally. While basal cell carcinoma predominates in fair-skinned populations, squamous cell carcinoma (SCC) is relatively more common among black populations. Chronic ulcers, including rare cases of lepromatous ulcers, may undergo malignant transformation into SCC. Case presentation: We present a cas...

Feb, 2026 pp. 124-129 274 views 177 downloads
11
Research Article DOI: 10.67579/njo.2026.1e4nz1ph

RECURRENT RECTAL ADENOCARCINOMA WITH KRAS MUTATION POST-MFOLFOX6/BEVACIZUMAB REMISSION: A CASE REPORT

Yusuf Tukur*, Abubakar M. Bello, Usman M. Aliyu, Oladapo B. Campbell, Aisha Mustapha, Abubakar Ibrahim Diggi, Yusuf Dantani, Shehu Salihu Umar

Background: This case report elucidates the clinical trajectory of a 41-year-old male diagnosed with low rectal adenocarcinoma, further complicated by pulmonary metastases, harboring a KRAS mutation, and characterized by microsatellite stability. Case Presentation: This patient demonstrated a significant and favorable response to neoadjuvant chemotherapy with a modified FOLFOX6 (mFOLFOX6) regimen ...

Feb, 2026 pp. 130-138 279 views 173 downloads
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