Articles

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42 articles
31
Research Article

SEX DISPARITY IN CANCER OCCURRENCE AND TREATMENT AMONG CANCER PATIENTS: A 2-YEAR RETROSPECTIVE STUDY OF THE ONCOLOGY UNIT, FEDERAL TEACHING HOSPITAL, GOMBE

Khadijat A. Bobbo*, Amina U. Babuga, Zubairu S. Rayyanu, Abdulrahman Adamu, Danladi A. Bojude

Background: Sexual disparity in cancer prevalence and treatment approaches is a crucial factor in achieving effective cancer treatment and management globally. This study aimed to investigate gender-specific patterns of cancer types and treatments among patients in Nigeria.Objective: To determine the prevalence of different cancer types and associated treatment modalities, highlighting any sexual ...

Jul, 2025 pp. 266-279 94 views 65 downloads
32
Research Article

PATTERN OF METASTATIC BREAST CANCER IN NIGERIA: A RETROSPECTIVE REVIEW OF CASES FROM NATIONAL HOSPITAL, ABUJA

Fatima Inno Uba*, Simeon C. Aruah, Festus Igbinoba, Rasaaq A. Oyesegun

Background: Metastatic Breast Cancer is a common presentation among breast cancer patients in Nigeria. There has been a slight decline in breast cancer mortality, which can be attributed both to the success of early detection programs and advances in treatment.Objective: To determine the pattern, sites, and outcomes of metastatic breast cancer among patients treated at the National Hospital, Abuja...

Jul, 2025 pp. 280-288 87 views 55 downloads
33
Research Article

EFFECTS OF ANDROGEN DEPRIVATION THERAPY ON FASTING BLOOD GLUCOSE IN PROSTATE CANCER PATIENTS AT A TEACHING HOSPITAL IN SOUTHWESTERN NIGERIA - A PILOT STUDY

Daluchukwu J. Obi*, Chiamaka G. Ehiedu, Abbas A Abdus-Salam, Atara I Ntekim, Augustine Takure, Ifeanyichukwu Nwanji, Olumide Farinre, Adeniyi A Adenipekun

Background: Prostate cancer is the most common cancer and the leading cause of cancer death in Nigerian men. There are many modalities of treatment of prostate cancer, among them is hormonal treatment with the use of androgen-deprivation therapy (ADT), and this has been reported to have effects on the blood glucose level, causing hyperglycaemia.Objective: To determine the effects of three-month ad...

Jul, 2025 pp. 289-299 84 views 50 downloads
34
Research Article

EFFECTS OF BRACHYTHERAPY BOOST ON PROSTATE CANCER TREATED WITH EXTERNAL BEAM RADIOTHERAPY: A PILOT STUDY

Abbas A. Abdus-salam*, Olabisi T. Ojo, Chiamaka G. Ehiedu, Maryam A. Bashir, Atara I Ntekim, Adewumi O. Alabi, Sharif A. Folorunso, Mutiu A Jimoh, Foluke O. Sarimiye, Adeniyi A Adenipekun

Background: Prostate cancer is the leading cause of cancer amongst men in Nigeria. External beam radiotherapy (EBRT) and high-dose rate brachytherapy (HDR-BT) play a significant role in the management of localised prostate cancer.Objective: This study compared the treatment outcome of the management of intermediate and high-risk localised prostate cancer patients using EBRT alone and EBRT + BT.Met...

Jul, 2025 pp. 300-312 96 views 59 downloads
35
Research Article

A PROGRESSIVE EMBRYONAL RHABDOMYOSARCOMA OF THE UTERINE CERVIX WITH RIGHT BREAST LUMP IN A 43-YEAR-OLD ADULT: A CASE REPORT

Amina I Dansani*, Tajudeen A. Olasinde, Olabisi T. Ojo, Aisha Mustapha, Shehu Abdullahi, Shehu Salihu Umar

Introduction: Embryonal Rhabdomyosarcoma is an uncommon type of sarcoma often seen in pediatric and adolescent patients, with the botryoid subtype being the most common. The incidence of this disease in adult females is 0.4% to 1% with the affected age group being patients in the third to fourth decade of life. It is rare in patients above 40 years in Nigeria.Case Presentation: We describe the cas...

Jul, 2025 pp. 313-320 105 views 65 downloads
36
Research Article

PRIMARY FEMUR NEUROBLASTOMA IN A 16-YEAR-OLD: A CASE REPORT

Adewumi O. Alabi*, Bright A. Igbinoba, Oluseyi K. Idowu, Kolawole O. Aramide, Nnamdi Orah, Mohammed Y.M. Habeebu, Opeyemi I. Olusunmade, Emmanuel E. Ojiebun

The incidence of neuroblastomas in individuals aged 10 and above is less than 10%. It is also associated with poor prognosis in older children and adults. This is a case report of a 16-year-old lady with pain and swelling in the left knee. The definitive diagnosis was neuroblastoma in the left distal femur after immunohistochemistry. The patient underwent surgery and chemotherapy. Extremity neurob...

Jul, 2025 pp. 321-327 102 views 58 downloads
37
Research Article

CASE REPORT: A SUCCESSFULLY TREATED MYCOSIS FUNGOIDES WITH CHOP CHEMOTHERAPY REGIMEN

Fatima I. Uba*

Introduction: Mycosis fungoides (MF) is a rare and aggressive form of cutaneous T-cell lymphoma (CTCL). It typically presents with skin lesions, but can progress to involve lymph nodes, blood and internal organs. Treatment options for MF are limited, and the disease often has a poor prognosis.Case Presentation: We report a case of a patient who presented with history of itching around the head and...

Jul, 2025 pp. 328-331 113 views 60 downloads
38
Research Article

A CASE REPORT OF IFOSFAMIDE INDUCED ENCEPHALOPATHY IN THE MANAGEMENT OF METASTATIC VULVAR LEIOMYOSARCOMA IN NATIONAL HOSPITAL ABUJA

Shagaya Uchechukwu Nneka, Ayuba Hannatu Usman*, Paul Emeka, Bello Abubakar Mohammed, Mohammed Nafisah Mamman, Kwapmi Nicholas, Umar Farouk Dalhat, Anosike Agbedo

Introduction: Ifosfamide induced encephalopathy (IIE) is not a common phenomenon and is under reported in our context. Its incidence ranges between 10 to 40% in developed settings. It comprises of a range of neuropsychiatric conditions such as confusion, disorientation, somnolence, agitation, hallucinations, lethargy, and seizures. With the extensive use of ifosfamide in oncology in the management...

Jul, 2025 pp. 332-336 88 views 62 downloads
39
Research Article

SYNCHRONOUS PRIMARY CERVICAL AND COLORECTAL CANCERS IN A 25-YEAR-OLD WOMAN

Charles Okwonna*, Nafisa B. Iliyasu, Ali Abba Tijjani, Sunday A. Adewuyi, Shehu Salihu Umar

Introduction: Synchronous cancer refers to two or more malignancies co-existing in a patient at the time of diagnosis or within 6 months of diagnosing the first. Cervical cancer is the commonest gynecological malignancy in Nigeria, while colorectal cancer the 4th commonest malignancy in Nigeria.Case Presentation: We present a 25-year-old grand multi-para who presented the hospital with a 20-month ...

Jul, 2025 pp. 337-343 86 views 42 downloads
40
Research Article

BREAST CANCER IN YOUNG ADULTS: A CASE SERIES

Ndidi Okunnuga*, Bamidele Alegbeleye, Adedotun Akinwande, Adetokunbo Okunnuga, Adewale Ayadi, Peter Ologunagba

Introduction: Breast cancer is the most common cancer among women globally. The age at presentation is crucial and determines the type, prognosis, or outcome of treatment. We report two cases of breast cancer in young adult patients due to its rarity and the need for clinicians to have a high index of suspicion while assessing any breast tumor in such patients.Case presentation: The clinical prese...

Jul, 2025 pp. 344-355 90 views 56 downloads