Research Article

PRIMARY FEMUR NEUROBLASTOMA IN A 16-YEAR-OLD: A CASE REPORT

1 Department of Radiation Biology, Radiotherapy & Radiodiagnosis, College of Medicine, University of Lagos, Lagos.
2 Oncology Unit, National Orthopaedic Hospital, Igbobi, Lagos.
3 Department of Anatomic and Molecular Pathology, College of Medicine, University of Lagos, Lagos.
4 Oncology Unit, National Orthopaedic Hospital, Igbobi, Lagos
5 NSIA-LUTH Cancer Centre, Lagos University Teaching Hospital, Idi Araba, Lagos
* Corresponding author: adewumioalabi@ngjoncology.com
Published: Jul, 2025
Pages: 321-327

Abstract

The incidence of neuroblastomas in individuals aged 10 and above is less than 10%. It is also associated with poor prognosis in older children and adults. This is a case report of a 16-year-old lady with pain and swelling in the left knee. The definitive diagnosis was neuroblastoma in the left distal femur after immunohistochemistry. The patient underwent surgery and chemotherapy. Extremity neuroblastoma, although rare, can occur even in long bones. High index of suspicion, early detection, appropriate surgical intervention, and chemotherapy can improve the prognosis. This report boosts the currently sparse literature on neuroblastomas in adolescents, especially with skeletal tissues as a primary site of lesion.