CASE REPORT: A SUCCESSFULLY TREATED MYCOSIS FUNGOIDES WITH CHOP CHEMOTHERAPY REGIMEN

Introduction: Mycosis fungoides (MF) is a rare and aggressive form of cutaneous T-cell lymphoma (CTCL). It typically presents with skin lesions, but can progress to involve lymph nodes, blood and internal organs. Treatment options for MF are limited, and the disease often has a poor prognosis.

Case Presentation: We report a case of a patient who presented with history of itching around the head and neck region of 28 months duration with mixed hypo pigmented and hyper pigmented maculopapular scaly patches. Multiple skin biopsies revealed cutaneous T-cell lymphoma and immunohistochemistry showed CD 20 negative disease. The patient responded to treatment with CHOP (Cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy regimen. Clinical condition was satisfactory on follow up visits.

Conclusion: Early detection and treatment of MF will provide a better prognosis and prolong the patient’s life expectancy. This case highlights the significance of recognizing blistering as a prodromal symptom for early detection and management of MF.